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  Whole genome sequences of a male and female supercentenarian, ages greater than 114 years 

  Sebastiani, Paola; Riva, Alberto; Montano, Monty; Pham, Phillip; Torkamani, Ali; Scherba, Eugene; Benson, Gary; Milton, Jacqueline N.; Baldwin, Clinton T.; Andersen, Stacy; Schork, Nicholas J.; Steinberg, Martin H.; Perls, Thomas T. (2011)

  Supercentenarians (age 110+ years old) generally delay or escape age-related diseases and disability well beyond the age of 100 and this exceptional survival is likely to be influenced by a genetic predisposition that ...
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  Design of the WHIP-PD study: a phase II, twelve-month, dual-site, randomized controlled trial evaluating the effects of a cognitive-behavioral approach for promoting enhanced walking activity using mobile health technology in people with Parkinson-disease 

  Rawson, K.S.; Cavanaugh, J.T.; Colon-Semenza, C.; DeAngelis, T.; Duncan, R.P.; Fulford, Daniel; LaValley, Michael P.; Mazzoni, P.; Nordahl, T.; Quintiliani, Lisa M.; Saint-Hilaire, Marie-Helene; Thomas, Cathi A.; Earhart, G.M.; Ellis, Theresa D. (2020-04-20)

  BACKGROUND: Parkinson disease (PD) is a debilitating and chronic neurodegenerative disease resulting in ambulation difficulties. Natural walking activity often declines early in disease progression despite the relative ...
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  Long-term yogurt consumption and risk of incident hypertension in adults 

  Buendia, Justin R.; Li, Yanping; Hu, Frank B.; Cabral, Howard J.; Bradlee, M. Loring; Quatromoni, Paula A.; Singer, Martha R.; Curhar, Gary C.; Moore, Lynn L. (LIPPINCOTT WILLIAMS & WILKINS, 2018-08-01)
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  Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model 

  Tagge, Chad A.; Fisher, Andrew M.; Minaeva, Olga V.; Gaudreau-Balderrama, Amanda; Moncaster, Juliet A.; Zhang, Xiao-Lei; Wojnarowicz, Mark W.; Casey, Noel; Lu, Haiyan; Kokiko-Cochran, Olga N.; Saman, Sudad; Ericsson, Maria; Onos, Kristen D.; Veksler, Ronel; Senatorov, Vladimir V.; Kondo, Asami; Zhou, Xiao Z.; Miry, Omid; Vose, Linnea R.; Gopaul, Katisha R.; Upreti, Chirag; Nowinski, Christopher J.; Cantu, Robert C.; Alvarez, Victor E.; Hildebrandt, Audrey M.; Franz, Erich S.; Konrad, Janusz; Hamilton, James A.; Hua, Ning; Tripodis, Yorghos; Anderson, Andrew T.; Howell, Gareth R.; Kaufer, Daniela; Hall, Garth F.; Lu, Kun P.; Ransohoff, Richard M.; Cleveland, Robin O.; Kowall, Neil W; Stein, Thor D.; Lamb, Bruce T.; Huber, Bertrand R.; Moss, William C.; Friedman, Alon; Stanton, Patric K.; McKee, Ann C.; Goldstein, Lee E (OXFORD UNIV PRESS, 2018-02-01)

  The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic encephalopathy, and the relationships between these disorders, are poorly understood. We examined post-mortem brains from teenage athletes ...
• PleioGRiP: Pleiotropic Genetic Risk Prediction via Bayesian model search and classification 

  Sebastiani, Paola; Hartley, Stephen (2012-11-16)

  The program PleioGRiP performs a genome-wide Bayesian model search to identify SNPs associated with a discrete phenotype, and uses SNPs ranked by Bayes factor to produce nested Bayesian classifiers. These classifiers can ...
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  Handling Linkage Disequilibrium in Qualitative Trait Linkage Analysis Using Dense SNPs: A Two-Step Strategy 

  Cho, Kelly; Dupuis, Josée (BioMed Central, 2009-8-10)

  BACKGROUND. In affected sibling pair linkage analysis, the presence of linkage disequilibrium (LD) has been shown to lead to overestimation of the number of alleles shared identity-by-descent (IBD) among sibling pairs when ...
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  Genetic Analysis Workshop 16: Strategies for Genome-Wide Association Study Analyses 

  Cupples, L. Adrienne; Beyene, Joseph; Bickeböller, Heike; Daw, E. Warwick; Fallin, M. Daniele; Gauderman, W. James; Ghosh, Saurabh; Goode, Ellen L.; Hauser, Elizabeth R.; Hinrichs, Anthony; Kent, Jack W.; Martin, Lisa J.; Martinez, Maria; Neuman, Rosalind J.; Province, Michael; Szymczak, Silke; Wilcox, Marsha A.; Ziegler, Andreas; MacCluer, Jean W.; Almasy, Laura (BioMed Central, 2009-12-15)
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  Handling Linkage Disequilibrium in Linkage Analysis Using Dense Single-Nucleotide Polymorphisms 

  Cho, Kelly; Yang, Qiong; Dupuis, Josée (BioMed Central, 2007-12-18)

  The presence of linkage disequilibrium violates the underlying assumption of linkage equilibrium in most traditional multipoint linkage approaches. Studies have shown that such violation leads to bias in qualitative trait ...
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  Genetics Analysis Workshop 16 Problem 2: tTe Framingham Heart Study Data 

  Cupples, L. Adrienne; Heard-Costa, Nancy; Lee, Monica; Atwood, Larry D. (BioMed Central, 2009-12-15)

  Genetic Analysis Workshop 16 (GAW16) Problem 2 presented data from the Framingham Heart Study (FHS), an observational, prospective study of risk factors for cardiovascular disease begun in 1948. Data have been collected ...
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  Genome-Wide Association and Linkage Analysis of Quantitative Traits: Comparison pf Likelihood-Ratio Test and Conditional Score Statistic 

  Hendricks, Audrey E; Zhu, Yanyan; Dupuis, Josée (BioMed Central, 2009-12-15)

  Over the past decade, genetic analysis has shifted from linkage studies, which identify broad regions containing putative trait loci, to genome-wide association studies, which detect the association of a marker with a ...

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